Same here. The tool does not work more often than it does. In previous Xcode 14 releases it worked quite well. But it can't find the simulator screen at all and run an audit for example. Screen reader works in a way when you select Mac>Simulator instead of Simulator

You can make a little sample app to check this. Add a sample pdf to your project, like this one: https://www.w3.org/WAI/ER/tests/xhtml/testfiles/resources/pdf/dummy.pdf. In UIKit create a viewController in your storyboard with a button that will open a UIDocumentInteractionController like this: @IBAction func openScreen() { let urlPath = Bundle.main.path(forResource: "dummy", ofType: "pdf")! let url = URL(filePath: urlPath) let interactionController = UIDocumentInteractionController(url: url) interactionController.delegate = self interactionController.presentPreview(animated: true) documentInteractionController = interactionController } func documentInteractionControllerViewControllerForPreview(_ controller: UIDocumentInteractionController) -> UIViewController { self } func documentInteractionControllerDidEndPreview(_ controller: UIDocumentInteractionController) { documentInteractionController = nil } Then connect a hardware keyboard via Bluetooth, turn on Full Keyboard Access in your Accessibility Settings and try to navigate with TAB and arrow keys through the screen.