Similar problem here: Macbook Pro 2019 Big Sur 11.6, USB-C Hub: https://www.amazon.com/gp/product/B08DHKMQ1D/ Hisense H8G as monitor 4K HDR 60hz HDMI connection Whenever my laptop wakes while attached to this hub AND this hub is connected to my Hisense H8G via HDMI, the fan spins up to top speed for 1-2 seconds and then crashes (kernel panic). Sometimes it happens without sleep/wake, but sleep/wake is the guaranteed way to make it happen. I'm convinced the problem is related solely to the display connection aspect of this connection. If I remove the HDMI cable, but keep the USB-C hub connected, the problem does not persist. I did not experience this on Catalina. This only occured once I upgraded to Big Sur. I confirmed the following things that were suggested above: Automatic Graphics Switching: off Power Nap: off I don't have any daisy chain or similar options on my H8G I don't have any DisplayPort or associated settings on my H8G