This is still a bug in Xcode 12.5 on macOS 11.4. Have had to kill the CoreAudio daemon multiple times per day for nearly a year now. The simulator audio output control is new to me, have it set to an unused output when I don't need audio from simulator. Hopefully it holds. Thanks @Choonghee for the tip!
Topic:
App & System Services
SubTopic:
Core OS
Tags: