We see the same behaviour with the Sophos Mac Endpoint product which uses the NETransparentProxyProvider subclass for its network extension and the CISC AnyConnect client which uses the NEFilterDataProvider.
When both are enabled and active, Safari will fail to connect to web.whatsapp.com and other sites that use websockets.
Google Chrome does not have a similar problem with the same configuration.
Topic:
App & System Services
SubTopic:
Networking
Tags: