If you have enough available storage on your system disk, you can set up dual booting to take macOS Sequoia for a spin. Here's a very good reference video: https://www.youtube.com/watch?v=xzUPFeat9U4 Otherwise, one can use an external SSD or flash drive. Just remember to perform a TimeMachine backup before attempting any of these solutions.

After a bit of research, it appears that one can run via the iOS simulator but one will receive errors when trying to run via My Mac or Xcode Previews.