As of Saturday, August 14, 2021 at 10:20 AM EDT, I have Microsoft Outlook running on a Monterey Beta 5. (1) I had Outlook v16.51 running under Monterey Beta 4. (2) After updating the macOS to Monterey Beta 5, upon launch Outlook v16.51 gave me a spinning beachball of death. (3) I force-quitted Outlook v16.51. (4) I launched Microsoft AutoUpdate v4.38, and from Advanced selected Beta Channel. (5) It showed that Outlook v16.52 was available among other updates for other Office apps. (6) I chose to update only Outlook. (7) The updating process went through and AutoUpdate showed that Outlook was updated to v16.52. (8) I launched Outlook v16.52. It now operates normally without the spinning beachball of death.