Dear markstrefford, I am experiencing a similar issue on iPhone 13 mini. It appears to me that the video element can only start playing following a user gesture (i.e. a play-button tap). function playButtonClick(){ video.play(); } I have also tried to delay the play() function by at least 2 seconds, but that did not work.

In Sequioa 15.2 I was able to get the keystrokes working by: Creating an "Application" in the Automator. Adding the "Run AppleScript" Action to it, containing the keystrokes. Export it to my user's Application folder. Import the new Application in Shortcuts and adding it to the Dock. Open Settings > Privacy & Security > Accessibility. Making sure that all three Automator, Shortcuts and the new Application were added and enabled. After a reboot it still works, but upon any change to the Shortcut (adding it to the Quick Actions for example) I have to disable and re-enable Shortcuts in Settings > Privacy & Security > Accessibility. Note: Running the Shortcut from the menu bar completes normally without sending the keystrokes (also without any blocking notification).