TL;DR, updating to Xcode 16.3 fixed it for me. This broke for me as well in Xcode 16.2, and I did the normal dance of reseting simulators, restarting Xcode, restarting computer, and nuking derived data, etc. etc. ... but once I upgraded to 16.3, everything works again

Same here... buildQueue.maxConcurrentOperationCount = .needMorePower buildQueue.qualityOfService = .tears

I'm having some of these same issues. What I have noticed is that debugging while connected to USB-C works great, however, it seems that once I physically disconnect and try to run on a simulator or another device, Xcode attempts to connect back to my default device over the network and totally gets stuck. Once it gets into this state, Xcode was stuck "Indexing Open Quickly Content" which prevented me from killing Xcode. Had to kill 9 it. Also, the "Connect via network" option is grayed out so I can't disable this functionality. All I want is debugging over USB-C most of the time.