Turned out that this is not a bug of the OS but the use of semanticContentAttribute in code which was set to .forceRightToLeft. Since iOS 15 VoiceOver is responding to that as well.

I experience the same for English (US and UK). Another issue is that it only announces euro's in English but not the cents.I use a NumberFormatter with currency style and usesGroupingSeparator = false. E.g., €1,645.45 is announced as "One thousand six hundred forty five euro's dot forty five". Do you experience the same? I would expect "One thousand six hundred forty five euro's and forty five cents"