Hi Kevin Thank you for looking into. Is the USB hub powered? No, the hub was not powered. are you seeing any activity on the bus when the iPad wakes up again? No we did not. You can find the latest activity reported in the logs in the case1_usbd_log.txt after 5 seconds of sleep: USBD Suspend : Remote Wakeup = 0 BUS RESET USBD Bus Reset: Full Speed did the working device fully power down the bus during sleep? The last event after the device goes to sleep is the Suspend event.