Some more findings below:
It seems that Apple supports the DeviceN color space model but not the Separation color space mode. The DeviceN model appears to support the concept of Spot Colors but I can't seem to find any details on how one much create a DeviceN color space using the Apple APIs.
https://developer.apple.com/documentation/coregraphics/cgcolorspacemodel
Topic:
App & System Services
SubTopic:
Networking
Tags: